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The Trx-interacting protein (TXNIP) promotes ferroptosis in mouse models of bronchopulmonary dysplasia [108] , cardiac ischemia/reperfusion injury [109] , sepsis-induced cardiomyopathy [110] , and polycystic ovary syndrome [111]
1 Patients were eligible for inclusion if they had a body mass index (BMI) of 30 kg/m2 or 27 kg/m2 with hypertension, dyslipidemia, obstructive sleep apnea, and/or cardiovascular disease
Clinically abandoned due to a rat carcinogenic signal (long-term hepatocarcinomas)
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