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One very small study found that people who used semaglutide had lower B12 levels, but these patients also had bariatric surgery prior to using semaglutideso its hard to say if using semaglutide would lead to a B12 deficiency, requiring additional B12

Amanda Kahn expressed her particular interest in MOTS-c because of its "potential role in mitochondrial biology and metabolic health," as mitochondrial dysfunction is associated with aging and many chronic diseases

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For physiological reasons, dietary vitamin B12 generally cannot cause hypercobalaminemia