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Standing up slowly, staying well hydrated, and avoiding skipping meals entirely can help

For many patients, this involves combination therapy using: PT-141 injections (Bremetide) to activate sexual desire and central arousal PDE5 inhibitors or compounded therapies like Erexafil to boost blood flow and erectile response Hormone replacement therapy is recommended if low testosterone is identified Sublingual medications for rapid-onset enhancement when needed This protocol also considers comorbidities such as high blood pressure, diabetes, or neurological conditions, ensuring that treatment is safe, effective, and aligned with broader health goals

Others may be able to gradually discontinue the medication under medical supervision after establishing sustainable lifestyle habits. Doctors emphasise that lasting weight management is not about relying on a single medicine

Acknowledgments We would like to acknowledge the researchers whose relevant works are cited in this review and all co-authors for their support