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Finally, establishing pharmacovigilance frameworks and core outcome sets with clinically meaningful thresholds will be essential to ensure safety, comparability, and regulatory readiness for antioxidant-based strategies in ASD
For example, one review analysis of 12 studies found that research participants who took an ALA supplement lost about 1.5 pounds more during the study periods (which averaged 14 weeks) than those who got placebos
Recent clinical guidelines increasingly recommend GLP-1RAs for patients with type 2 diabetes who have established atherosclerotic cardiovascular disease or are at high cardiovascular risk, regardless of baseline hemoglobin A1c levels
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