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Clinical trials that tested rapid escalation protocols showed higher dropout rates because of intolerable GI side effects

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Individual outcomes may vary depending on factors lik

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Diabetologia 52:1730 Knowler WC, Barrett-Connor E, Fowler SE et al (2002) Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin

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These include Alzheimers Disease, Infertility, Depression, and Diabetes

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