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A regulated form of necrosis, known as necroptosis, is a caspase-independent cell death mechanism that displays typical features of necrosis, including morphological alterations, subcellular changes, and metabolic dysfunction
doi:10.1002/ana.23594
A new derivate of DOX, 4-acetyl-2-nitro-benzenesulfonyl doxorubicin (ANS-DOX) was synthesized and shown to be converted into DOX by MGST1 and GSTA1-1, whereas no activity was observed for GSTP1-1 128
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