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As GLP-1 therapies become a long-term cornerstone in diabetes care, monitoring patients on these treatments is gaining renewed attention

Supported by numerous randomized controlled trials for knee osteoarthritis, tennis elbow, Achilles tendinopathy, and more

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The resulting mitochondrial stress activates key innate immune pathways, including cGAS-STING, TLR9, and NLRP3 inflammasome signaling, which collectively determine the balance between protective immunity and immunopathology (Xian et al., 2022)