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Clinical trials have demonstrated weight loss ranging from approximately 10% with GLP-1 agents at weight management doses (e.g., semaglutide 2.4 mg in the STEP trials) to over 20% with tirzepatide at higher doses (SURMOUNT trials)
For children, the stakes are particularly high
In both study groups a significant decrease of serum aldosterone and plasma renin concentration was observed after placebo as well as after liraglutide injection
This increased HGH level enhances metabolic activity, supports muscle growth, and reduces body fat, contributing to weight loss and improved body composition
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